Is TTreeCache needed using Proxies?

Dear ROOT experts,

I am using the MakeProxy() method to deal with super-efficient variable access.
I think it is great and works 99% of the time without any effort from the user side, I just wonder: does it make sense to use the TTreeCache optimizations (cache size, learning entries and so on) in this context? Or are the generated proxies already able to efficiently cache the events?

thank you very much in advance.